Mae Jemison

Publicity headshot for Mae Jemison Endeavour STS-47 patch
Endeavour STS-47 mission patch

The first African American woman astronaut was Dr. Mae C. Jemison, M.D.  She was an investigator with the payload Spacelab of Space Shuttle Endeavour mission STS-47 from September 12-20, 1992.  Her work focused on the effect of zero gravity on bone density.